Examples:
Research Skills: http://goo.gl/svRNX
NFL Statistics: http://goo.gl/HRTZJ
Penguins: http://goo.gl/Y2Xoc
Muscles and Tissue: http://goo.gl/Z7RDb

Sample Activities:
Social Studies: http://goo.gl/maps/wLsg
ELA/R: http://goo.gl/maps/NYAG
Math: http://goo.gl/maps/Zpim
Science: http://goo.gl/maps/G4iB

Google Earth Lessons
http://www.gelessons.com/lessons/

Real World Math - Using Google Earth in the Math Curriculum
http://www.realworldmath.org

Google Historical Voyages and Events
http://homepage.mac.com/larow2/Voyages/index.html

Dave Rumsey Map Collection

Google Earth Lesson Plans
http://sitescontent.google.com/google-earth-for-educators/classroom-resources/lesson-plan-library
From Google Classroom Resources

All About Me - Students will create a geographic organizer for important events in their lives.
AllAboutMeSAS.pdf
From The Digital Goonies

Other ideas for activities using Google Earth (or Maps!)
GoogleEarthActivityTypes.pdf
From The Digital Goonies